Microfluidic Devices with Onboard Sensors for Data Collection

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Title Microfluidic Devices with Onboard Sensors for Data Collection
Summary Integrate sensors to microfluidic devices for data collection
Keywords Microfluidics; Data Collection; Lab-on-Chip; Biology; Embedded Systems
TimeFrame November 2019 - 6 Months
References https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0224492

https://pubs.rsc.org/en/content/articlelanding/2016/lc/c6lc00562d/unauth#!divAbstract"https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0224492

https://pubs.rsc.org/en/content/articlelanding/2016/lc/c6lc00562d/unauth#!divAbstract" cannot be used as a page name in this wiki.

Prerequisites None
Author Ross Friel
Supervisor Ross Friel
Level Flexible
Status Open

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Research Question:

The question is can we integrate sensors into 3D Printed microfluidic devices and use these for relevant data collection with regards to biological x-ray analysis applications.

This project is more hardware related in that it is a hands-on experimental device manufacture project for experimental usage. There is a software aspect as the use of a microcontroller (e.g. Arduino) would be necessary to interpret electrical data from the device sensors.

Work packages: 1) Review the area via literature, supervisor discussion and collaborators to gain the necessary background in the area. Document this and generate specific thesis objectives to answer the research question and act as a measure of success. 2) Modify existing 3D Printed microfluidic device designs for sensor integration and relevant data output. Identify suitable sensors for the necessary data collection. 3) Produce devices and integrate sensors. 4) Test the devices in bench-top experiments to run relevant biological (non-hazardous) material through them whilst collecting and interpreting relevant data.

Bonus Work Package: 5) Experiment with the device at the MAX IV synchrotron to collect data in a 'real' environment/experiment.

Deliverables:

  • Suitable literature review
  • Experimental 3D Printed microfluidic device with data collection functionality.
  • Experimental data showing what was collected.
  • Thesis describing in detail the objectives, reasoning on technological choices, clearly presented data for results and discussion.

Outcomes:

  • Real hands-on research experience for the student.
  • Further development of microfluidic devices for use at synchrotrons.
  • Beneficial work to increase Halmstad Universities research profile.
  • Contributing bonus work to the SSF funded project 'AdaptoCell'.