| Abstract
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<p>In the cochlea of the inner ear, … <p>In the cochlea of the inner ear, outer hair cells (OHC) together with the local passive structures of the tectorial and basilar membranes comprise non-linear resonance circuits with the local and central (afferent–efferent) feedback. The characteristics of these circuits and their control possibilities depend on the mechanomotility of the OHC. The main element of our functional model of the OHC is the mechanomotility circuit with the general transfer characteristic y = k tanh(x − a). The parameter k of this characteristic reflects the axial stiffness of the OHC, and the parameter a working position of the hair bundle. The efferent synaptic signals act on the parameter k directly and on the parameter a indirectly through changes in the membrane potential. The dependences of the sensitivity and selectivity on changes in the parameters a and k are obtained by the computer simulation. Functioning of the model at low-level input signals is linear. Due to the non-linearity of the transfer characteristic of the mechanomotility circuit the high-level signals are compressed. For the adaptation and efferent control, however, the transfer characteristic with respect to the initial operating point should be asymmetrical (a > 0). The asymmetry relies on the deflection of the hair bundle from the axis of the OHC.</p>bundle from the axis of the OHC.</p>
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| Author
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Antanas Stasiunas +
, Antanas Verikas +
, Marija Bacauskiene +
, Rimvydas Miliauskas +
, Natalija Stasiuniene +
, Kerstin Malmqvist +
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| DOI
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http://dx.doi.org/10.1016/j.medengphy.2005.03.002 +
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| Diva
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http://hh.diva-portal.org/smash/record.jsf?searchId=1&pid=diva2:237436
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| EndPage
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789 +
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| Issue
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9 +
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| Journal
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Medical Engineering and Physics +
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| PublicationType
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Journal Paper +
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| Publisher
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Elsevier +
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| StartPage
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780 +
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| Title
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Compression, adaptation and efferent control in a revised outer hair cell functional model +
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| Volume
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27 +
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| Year
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2005 +
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| Has queryThis property is a special property in this wiki.
|
Publications:Compression, adaptation and efferent control in a revised outer hair cell functional model +
, Publications:Compression, adaptation and efferent control in a revised outer hair cell functional model +
, Publications:Compression, adaptation and efferent control in a revised outer hair cell functional model +
, Publications:Compression, adaptation and efferent control in a revised outer hair cell functional model +
, Publications:Compression, adaptation and efferent control in a revised outer hair cell functional model +
, Publications:Compression, adaptation and efferent control in a revised outer hair cell functional model +
, Publications:Compression, adaptation and efferent control in a revised outer hair cell functional model +
, Publications:Compression, adaptation and efferent control in a revised outer hair cell functional model +
, Publications:Compression, adaptation and efferent control in a revised outer hair cell functional model +
, Publications:Compression, adaptation and efferent control in a revised outer hair cell functional model +
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| Categories |
Publication +
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| Modification dateThis property is a special property in this wiki.
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30 September 2016 20:40:22 +
|
